The KNG1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to BK, HMWK, Kininogen 1, and KNG1. This antibody recognizes Human antigen. The KNG1 Antibody has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
Kininogens are inhibitors of thiol proteases. Kininogen 1 plays important role in Kinin-kallikrein system. This gene is translated into High-molecular weight kininogen (HMWK) and low-molecular weight kininogen (LMWK) after alternative splicing. HMWK is produced by the liver together with prekallikrein. It acts mainly as a cofactor on coagulation and inflammation, and has no intrinsic catalytic activity. LMWK is produced locally by numerous tissues, and secreted together with tissue kallikrein. 11926-1-AP was generated against N-terminal 300 aa of HMW kininogen. It can bind both HMW and LMW kiniogen